First-tier next-generation sequencing for newborn screening: An important role for biochemical second-tier testing

There is discussion of expanding newborn screening (NBS) through the use of genomic sequence data; yet, challenges remain in the interpretation of DNA variants.Population-level DNA variant databases are available, and it is possible to estimate the number of newborns who would be flagged as having a risk for a genetic disease (including rare varian

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Optimization of Work Schedules Executed using the Flow Shop Model, Assuming Multitasking Performed by Work Crews

The problem described in this paper deals with construction project Jigsaw Puzzle scheduling for multi-object projects.The use of the flow shop model allows for quick execution through optimal, simultaneous means of production.The correct order of tasks according to assumed criteria is the subject of a lot of research.In this paper, we have focused

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